Tetrapyrroles and derivatives
Abcam L-threo-PDMP, 10MG
MW 427.03 g/mol, Purity >98%. Enantiomer of D-threo-PDMP (Asc 4052). Activates glycosyltransferases for ganglioside biosynthesis. Antineurodegenerative properties. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam HTMT (Histamine trifluoromethyl toluidide) dimaleate, H1/H2 receptor agonist, 10MG
MW 628.6 Da, Purity >99%. H1/H2 receptor agonist (Ki = 1.2 µM). More potent than histamine (ab120734). Activates IP3/Ca2+ signaling and induces proliferation of small cholangiocytes. Active *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (±)-Miconazole nitrate, Imidazole antifungal agent, 1G
MW 479.1 Da, Purity >99%. Imidazole antifungal agent. Inhibits fungal membrane ergosterol biosynthesis. Increases reactive oxygen species production.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Chlorin e6 trimethyl ester | 35038-32-5 | MFCD09838560 | 99.8% | 638.75 | C37H42N4O6 | 5 MG
Chlorin e6 trimethyl ester is a methyl pheophorbide-A derivative photosensitizer used in photodynamic therapy research and photophysics studies. It is supplied as a high-purity solid for in-vitro use and formulation, with defined solubility and storage recommendations to preserve stability.
- High reported purity (99.8%) suitable for research applications.
- Photosensitizer used in photodynamic therapy and photophysics studies.
- Soluble in DMSO at about 10 mg/mL with sonication and warming to 60°C; hygroscopic DMSO can affect solubility.
- Powder storage: -20°C (up to 3 years) or 4°C (up to 2 years); in solvent: -80°C (6 months) or -20°C (1 month).
- Provided as a brown to black solid appropriate for formulation and analytical work.
![Abcam [Pyr1]-Apelin 13, endogenous apelin receptor (APJ) agonist, 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502583378.JPG-250.jpg)
Abcam [Pyr1]-Apelin 13, endogenous apelin receptor (APJ) agonist, 1MG
MW 1533.8 Da, Purity >95%. [Pyr1]-Apelin 13, endogenous apelin receptor (APJ) agonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Chlorin e6 trisodium | 72984-36-2 | 98.7% | 662.62 | C34H33N4Na3O6 | 5mg
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation enabling real-time identification of tumor boundaries and progression Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3]
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 50mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Cayman Chemical MethylcobalamIn 100mg
An analog of vitamin B12 with diverse neurological activities; promotes neurite outgrowth and survival in primary CGN and DRG cells and activation of ERK1/2 and Akt from 0.1-100 µM; improves sensory function in a pinch test and increases toe spreading in a rat model of sciatic nerve injury at 1 mg/kg per day; decreases the number of atypical mitochondria in the sciatic nerve and reduces vincristine-induced mechanical allodynia and thermal hyperalgesia in a rat model of neuropathic pain; reduces muscle weakness and forelimb contracture and increases bicep muscle weight and the number of musculocutaneous nerves in the wobbler mouse model of ALS; enhances the recovery of compound muscle action potentials and motor end plate innervation and decreases the time to sticker removal in the sticker removal grooming test in a rat model of bicep ulnar to musculocutaneous nerve transfer
Abcam MPEP hydrochloride, mGlu5 antagonist, 10MG
MW 229.7 Da, Purity >99%. Subtype selective and potent non-competitive mGlu₅ antagonist (IC₅₀ = 36 nM). Central effects following systemic administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam MPEP hydrochloride, mGlu5 antagonist, 50MG
MW 229.7 Da, Purity >99%. Subtype selective and potent non-competitive mGlu₅ antagonist (IC₅₀ = 36 nM). Central effects following systemic administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Necrostatin-1, necroptosis inhibitor, 5MG
MW 259.33 Da, Purity >99%. Potent, specific necroptosis inhibitor (EC₅₀ = 490 nM). Selective allosteric inhibitor of death domain receptor-associated adaptor kinase RIP1 in vitro (EC₅₀ = 182 nM). Caspase independent, programmed necrosis pathway.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Necrostatin-1, necroptosis inhibitor, 50MG
MW 259.33 Da, Purity >99%. Potent, specific necroptosis inhibitor (EC₅₀ = 490 nM). Selective allosteric inhibitor of death domain receptor-associated adaptor kinase RIP1 in vitro (EC₅₀ = 182 nM). Caspase independent, programmed necrosis pathway.
The product is subject to the following: Abcam Restricted Use Statement